answers to
frequently asked questions

Below are answers to some frequently asked questions about MARINOL.

Dronabinol, the active ingredient in MARINOL (dronabinol) capsules, is synthetic delta-9-tetrahydrocannabinol (THC). Delta-9-tetrahydrocannabinol is also a naturally occurring component of Cannabis sativa L. (marijuana). Drug tests are designed to detect delta-9-tetrahydrocannabinol (THC), among other chemicals.2
Yes, MARINOL is contraindicated in patients with a history of hypersensitivity reaction to dronabinol or sesame oil. Reported hypersensitivity reactions to dronabinol capsules include lip swelling, hives, disseminated rash, oral lesions, skin burning, flushing, and throat tightness.
A cannabinoid dose-related “high” (easy laughing, elation, and heightened awareness) has been reported by patients receiving MARINOL in both the antiemetic (24%) and the lower-dose appetite stimulant clinical trials (8%).1
MARINOL has been associated with cognitive impairment and altered mental state. Elderly patients may be more sensitive to the neurological and psychoactive effects of MARINOL. MARINOL may impair the mental and/or physical abilities required for the performance of hazardous tasks. Patients should not operate motor vehicles or other dangerous machinery until they are reasonabley certain that MARINOL does not affect them adversely.
MARINOL is a Schedule III controlled substance and contains dronabinol, the main psychoactive component in marijuana. Injestion of high doses of dronabinol increases the risk of psychiatric adverse reactions if abused or misused, while continued use can lead to addiction.
Some insurance plans may require a prior authorization before MARINOL can be dispensed. Contact the specific healthcare plan to review product coverage and approval requirements.
Some insurance plans may have restrictions on the use of MARINOL. Contact the specific healthcare plan to review product coverage.
MARINOL should be stored in a cool place (46-59°F; 8-15°C) or in the refrigerator. The capsules should not be frozen. Heat or moisture may cause MARINOL to break down or stick together, so it’s advisable to keep this medicine away from heat and direct light, and potentially damp places such as the bathroom or near the kitchen sink.1

A prescription for controlled substances in Schedules III, IV, and V issued by a practitioner may be communicated either orally, in writing, or by facsimile to the pharmacist and may be refilled if so authorized on the prescription or by call-in.3

Refills: Schedule III and IV controlled substances may be refilled if authorized on the prescription. However, the prescription may be refilled only up to five times within 6 months after the date on which the prescription was issued. After five refills or after 6 months, whichever occurs first, a new prescription is required.3

Facsimile Prescriptions for Schedule III-V Substances: Prescriptions for Schedules III-V controlled substances may be transmitted by facsimile from the practitioner or an employee or agent of the individual practitioner to the dispensing pharmacy. The facsimile is considered to be equivalent to an original prescription.3

Telephone Authorization for Schedule III-V Prescriptions: A pharmacist may dispense a controlled substance listed in Schedule III, IV, or V pursuant to an oral prescription made by an individual practitioner and promptly reduced to writing by the pharmacist containing all information required for a valid prescription, except for the signature of the practitioner.3

Delivery of a Controlled Substance to Persons Outside the US: Controlled substances that are dispensed pursuant to a legitimate prescription may not be delivered or shipped to individuals in another country. Any such delivery or shipment is a prohibited export under the Controlled Substances Act.3

Yes, there is an approved generic version of MARINOL.