Is MARINOL safe?

MARINOL has been proven to be safe and generally well tolerated.

The most frequently reported side effects during clinical studies involved the nervous system and included dizziness, feelings of exaggerated happiness, paranoid reaction, drowsiness, and thinking abnormally

Be sure that there is a responsible person nearby when you first start taking MARINOL (or if your health care professional decides to change your dose) in case any side effects occur.

Do not drive a car or operate machinery until you know how MARINOL affects you
There is a potential for central nervous system effects such as dizziness, drowsiness, and confusion
- The effects you get from MARINOL are determined in large part by the amount of medicine you take. These effects can vary considerably from one patient to another

While taking MARINOL, exercise caution when also taking sedatives, hypnotics, or other mind-altering substances, or when drinking alcohol as these may make it more likely for you to experience CNS side effects

Your health care professional will work closely with you to determine the dose of MARINOL that is best for you.

Your MARINOL dosage may need to be adjusted to maximize its benefits or to decrease any side effects
Depending on your dose, you’ll often find that CNS side effects (if they occur at all) generally decrease or stop after you’ve taken MARINOL for 1 to 3 days
Your health care professional may suggest other ways (such as reducing the dose or taking MARINOL in the evening or at bedtime) to minimize any side effects you may notice

MARINOL is unlikely to lead to abuse and addiction—a fact the federal government has formally recognized.

MARINOL meets high quality standards and contains consistent levels of delta-9-tetrahydrocannabinol (delta-9-THC)
- In contrast, the delta-9-THC in marijuana can vary from plant to plant and even from leaf to leaf
- Ideas for important medicines have originated from plants (including MARINOL). Aspirin from willow bark and the cancer drug paclitaxel from the Pacific yew tree are just two examples

Please read the relevant Patient Information for MARINOL, including precautions and adverse effects.

Next: What should I tell my health care team before taking MARINOL?

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