MARINOL (dronabinol) Capsules: Used for loss of appetite associated with weight loss in patients with AIDS.

Your doctor may prescribe an appetite stimulant such as MARINOL capsules. Increasing your appetite is the first step in improving your nutritional status. How, what, and when you eat are also very important. MARINOL is used for loss of appetite associated with weight loss in people with acquired immune deficiency syndrome (AIDS). MARINOL is in a class of medications called cannabinoids.

MARINOL Capsules contain man-made dronabinol (THC). THC is also a naturally occuring component of Cannabis sativa L. (marijuana).

Information about using MARINOL Capsules

MARINOL Capsules should be taken exactly as directed by your doctor and indicated on the prescription label. You will most likely start therapy by taking one white capsule (2.5 mg) of MARINOL Capsules twice daily, before lunch and supper. Your doctor may adjust your MARINOL Capsules dosage if needed to maximize its effect or to decrease any side effects.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double your dose. MARINOL Capsules must be swallowed whole to work effectively. Do not crush or chew the capsules.

It is important not to take sedatives, hypnotics, other mind altering substances, or alcohol, while taking MARINOL Capsules without notifying your healthcare providers (physician, pharmacists, and nurses). Do not drive or attempt other activities requiring full alertness while taking MARINOL Capsules. Your doctor will advise when you may resume these activities.

Your doctor and pharmacist should be made aware of any other prescription medications or over-the-counter products you may be taking, as they could affect the way you respond to MARINOL Capsules.

Remember to keep this and all other medication out of the reach of children.

MARINOL Use and Important Safety Information

USE1,2

MARINOL is used for loss of appetite associated with weight loss in patients with AIDS.

IMPORTANT SAFETY INFORMATION1,2

MARINOL should not be used if you are allergic to dronabinol or any of its ingredients, including marijuana and sesame oil.

You should not drive, operate machinery, or engage in any hazardous activity until you know how this medication affects you and until you are sure you can perform such tasks safely.

While taking MARINOL, do not drink alcohol, smoke marijuana, or take other drugs that have an effect on the central nervous system such as Valium® (diazepam), Librium® (chlordiazepoxide), Xanax® (alprazolam), Seconal® (secobarbital), Nembutal® (pentobarbital), or phenobarbital. It is important to tell your doctor or pharmacist about all other prescription and non-prescription medicines you are taking as MARINOL use may change the effect of these medicines.

Be sure to tell your doctor if you:

  • Have a history of seizure disorders and/or seizure-like activity because this has occurred in people taking MARINOL. If you experience a seizure, stop taking MARINOL and seek medical attention immediately
  • Have or had heart problems because you may experience low or high blood pressure, fainting, or fast heart rate
  • Have current issues with or a history of drug and alcohol abuse
  • Have or had mental health problems (mania, depression, schizophrenia) because MARINOL may make these illnesses worse
  • Are pregnant or nursing or become pregnant

MARINOL should be used with caution in pregnancy, nursing mothers or children because it has not been studied in these populations.

Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug.

You may experience changes in mood or have other effects when first taking MARINOL. Be sure that there is a responsible person nearby when you first take MARINOL or when there is an adjustment in your dose.

Do not smoke marijuana while using MARINOL. This can cause an overdose.

Adverse effects you may experience include feeling high, dizziness, confusion, or sleepiness.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088 (1-800-332-1088).

If you cannot afford your medication, contact: www.pparx.org or call the toll-free phone number (1-888-4PPA-NOW) (1-888-477-2669) for assistance.

References: 1. MARINOL [prescribing information]. 2. MARINOL [patient information].

1301985-1214105

Safety Considerations

MARINOL should not be used if you are allergic to dronabinol or any of its ingredients, including marijuana and sesame oil. You should not drive or operate machinery until you know how MARINOL affects you. While taking MARINOL, do not drink alcohol, smoke marijuana, or take other drugs that have an effect on the central nervous system such as sedatives or hypnotics. Tell your doctor if you have or had in the past, any of the following: heart problems; mental health problems; issues with drug or alcohol abuse; seizure disorders and/or seizure-like activity. Also tell your doctor if you are or become pregnant or are nursing.

Use1,2

MARINOL is used for loss of appetite associated with weight loss in patients with AIDS.